Analytical Data
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基因名
IL-36 gamma
- Application
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别名
IL-1-related protein 2, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 9, IL-1F9
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种属
Human
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表达系统
E. coli
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标签
Tag Free
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纯度
>95% as determined by SDS-PAGE
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蛋白编号
Q9NZH8
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表达区间
1-169aa
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分子量
18.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
IL-36 gamma, also known as interleukin-36 gamma, is a cytokine belonging to the IL-1 family and plays a critical role in the immune response, particularly in the context of inflammatory diseases and skin conditions. This protein has garnered significant interest due to its involvement in modulating both innate and adaptive immune responses. Research indicates that IL-36 gamma is highly expressed in inflammatory conditions such as psoriasis, where it contributes to the proliferation of keratinocytes and the activation of immune cells. The cytokine has been linked to the pathogenesis of various autoimmune diseases, making it a potential target for therapeutic interventions. In recent years, recombinant IL-36 gamma proteins have been developed for research purposes, allowing scientists to investigate their biological functions and therapeutic potential. These studies aim to elucidate the mechanisms by which IL-36 gamma influences inflammation and identify possible pathways for intervention in disease processes. By better understanding this cytokine's role, researchers hope to develop novel treatments that could alleviate symptoms in conditions driven by excessive inflammation, thereby improving patient outcomes. Therefore, exploring IL-36 gamma through recombinant protein studies is crucial for advancing our knowledge of immune regulation and developing targeted therapies for inflammatory diseases.












