Analytical Data
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Gene name
FOXF2
- Application
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Alternative Names
FKHL6; FREAC2; FOX-F2; Forkhead-related activator 2; Forkhead-related transcription factor 2; Forkhead-related protein FKHL6
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O54743
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Expression Region
Leu203~Met446
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Molecular Weight
33kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FOXF2, a member of the Forkhead box (FOX) transcription factor family, plays a crucial role in various biological processes, including embryonic development, tissue repair, and cellular differentiation. Research has highlighted its involvement in the regulation of genes associated with epithelial cell function and development of the lung, where it has been linked to the formation of the alveoli and the maintenance of airway epithelial integrity. Additionally, aberrations in FOXF2 expression have been implicated in several diseases, such as fibrosis and various cancers, including lung and breast cancer, where its dysregulation affects tumor progression and metastasis. The study of FOXF2 recombinant protein is vital for elucidating its functional mechanisms and interactions at the molecular level, offering insights into its role as a potential biomarker or therapeutic target. By producing and characterizing FOXF2 recombinant protein, researchers can analyze its binding affinities, post-translational modifications, and regulatory pathways, thereby contributing to a clearer understanding of its biological significance and potential applications in regenerative medicine and cancer therapy. Understanding FOXF2's structure-function relationship through recombinant technology can pave the way for innovative strategies to manipulate its activity in clinical settings, enhancing both diagnostic and therapeutic approaches in diseases associated with altered FOXF2 function.
