Analytical Data
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基因名
CDH16
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简介
CDH16, a calcium-dependent cell adhesion protein, belongs to the cadherin family. It exhibits homophilic interactions, potentially contributing to cell-type sorting and regulating cell-cell adhesions for cellular organization. CDH16 Protein, Human (HEK293, His) is the recombinant human-derived CDH16 protein, expressed by HEK293 , with C-His labeled tag.
- Application
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别名
Cadherin-16; Ksp-cadherin; CDH16
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种属
Human
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表达系统
HEK293
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标签
C-8*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75309
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表达区间
K19-A786
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蛋白长度
Extracellular Domain
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分子量
90-110 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CDH16, also known as cadherin-16, is a member of the cadherin superfamily, which plays a crucial role in cell adhesion and signaling within the kidney and other tissues. It is primarily expressed in the renal collecting duct system and is believed to be involved in the regulation of kidney development and function. Dysregulation of CDH16 has been implicated in various renal disorders, including nephrogenic diabetes insipidus and other conditions affecting water and electrolyte balance. Given its significance in kidney physiology, the recombinant expression and characterization of CDH16 protein have garnered considerable interest in research settings. Scientists aim to elucidate its structural properties, interaction mechanisms, and functional roles in cellular processes through recombinant techniques. This involves using recombinant DNA technology to produce CDH16 in suitable expression systems, allowing for extensive biochemical and biophysical analyses. Understanding the structure-function relationship of CDH16 could pave the way for novel therapeutic strategies targeting renal diseases and provide insights into cadherin-mediated cellular interactions in other biological contexts. Additionally, studying the reconstructions of CDH16 could facilitate the development of specific inhibitors or enhancers that can modulate its activity, thereby influencing kidney function and potentially addressing various pathologies linked to its dysfunction. As such, the investigation of CDH16 recombinant protein serves as a crucial step toward unraveling its biological significance and therapeutic potential in the field of nephrology and beyond.
