Analytical Data
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Gene name
TMPRSS5
- Application
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Alternative Names
Spinesin
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H3S3
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Expression Region
Tyr71~Leu457
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Molecular Weight
46kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TMPRSS5 (Transmembrane Protease, Serine 5) is a type II transmembrane serine protease involved in several physiological and pathological processes, including cell signaling, inflammation, and viral entry. Research on TMPRSS5 has gained attention due to its role in facilitating the entry of certain viruses, such as coronaviruses, into host cells by activating viral glycoproteins. The cleavage activity of TMPRSS5 is critical in the context of viral infections, making it a potential target for therapeutic interventions. Additionally, studies have suggested that TMPRSS5 may be implicated in various cancers and other diseases where protease activity is deregulated. Its expression patterns and functional significance in different tissues provide insights into its diverse roles in health and disease. Understanding the structure and function of TMPRSS5, particularly through the development of recombinant proteins, can aid in elucidating its mechanisms of action, paving the way for novel therapeutic strategies and insights into viral pathogenesis and tumor biology. This growing body of research emphasizes the importance of TMPRSS5 as a key player in both viral entry mechanisms and disease processes, warranting further investigation into its potential as a biomarker or therapeutic target.
