Analytical Data
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基因名
NFIB
- Application
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别名
NFI-RED; NFIB2; NFIB3; CCAAT-box-binding transcription factor; TGGCA-binding protein
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O00712
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表达区间
Met1~Gln233
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分子量
57.0kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NFIB (Nuclear Factor I B) is a transcription factor that plays a pivotal role in various biological processes, including cellular development, differentiation, and response to stress. Research into NFIB has gained momentum due to its implications in several diseases, particularly in cancer. Studies have shown that NFIB is aberrantly expressed in various tumor types, contributing to oncogenesis by promoting cell proliferation, survival, and migration. Additionally, NFIB interacts with other signaling pathways and transcription factors, influencing the tumor microenvironment and immune response. Given its involvement in these critical mechanisms, NFIB has emerged as a potential therapeutic target, prompting investigations into its structure, function, and regulatory networks. Understanding the molecular mechanisms of NFIB could lead to novel strategies for cancer treatment and shed light on its role in normal physiology and disease. Researchers are employing various techniques, including molecular biology, genomics, and bioinformatics, to unravel NFIB's complex regulatory roles and identify downstream targets that may provide insight into its therapeutic potential. The ongoing studies focus on defining the specific contexts in which NFIB acts, how its activity is regulated, and its interactions with other cellular components, which are crucial for developing targeted interventions in diseases characterized by NFIB dysregulation. This research not only expands our understanding of NFIB's biological functions but also enhances the potential for developing innovative treatment strategies for cancer and other NFIB-related disorders.












