Analytical Data
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Gene name
COPb1
- Application
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Alternative Names
Beta-COP; Beta-coat protein
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Species
Human
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P53618
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Expression Region
Met1~Ile177
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Molecular Weight
50kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
COPb1 (Coat Protein Complex b1) is a crucial component of the vesicular transport system in eukaryotic cells, playing a significant role in the sorting and trafficking of proteins within the cell. The COPb1 complex facilitates the transport of proteins from the endoplasmic reticulum to the Golgi apparatus, ensuring that proteins are properly modified and dispatched to their final destinations. Research has indicated that disruptions in COPb1 function can lead to various cellular dysfunctions and diseases, including neurodegenerative disorders and cancer. Given its essential role in intracellular transport, COPb1 has emerged as a promising target for therapeutic interventions. The study of COPb1 recombinant proteins aims to elucidate the structure-function relationship and the molecular mechanisms underlying COPb1-mediated transport processes. By producing COPb1 in a recombinant form, researchers can perform detailed functional assays and structural analyses that are crucial for understanding its interactions with other cellular components. Additionally, the development of COPb1 inhibitors or modulators could pave the way for innovative treatments for diseases associated with protein misfolding and transport abnormalities. The growing interest in COPb1 is reflective of the broader scientific trend towards deciphering the complexities of intracellular trafficking systems, which hold significant implications for cellular health and disease. Thus, the exploration of COPb1 recombinant proteins represents an important step in advancing our comprehension of protein transport mechanisms and their potential therapeutic applications.
