Analytical Data
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Gene name
BEST3
- Application
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Alternative Names
VMD2L3; Vitelliform Macular Dystrophy 2-Like 3
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Species
Mouse
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6H1V1
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Expression Region
Glu507~Phe669
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Molecular Weight
50&55kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of BEST3 (Bestrophin-3) recombinant proteins has gained significant attention due to its implications in both physiological and pathological processes. BEST3 is a member of the bestrophin family of proteins, which are integral membrane proteins primarily associated with the regulation of ion channels in various tissues, including the retina and the gastrointestinal tract. Mutations in the BEST3 gene are linked to various ocular diseases, such as Best disease and other forms of macular degeneration, highlighting its vital role in retinal health. Furthermore, BEST3 has been implicated in cellular signaling pathways and calcium homeostasis, significantly influencing cell excitability and ion transport. As research progresses, the recombinant expression of BEST3 protein is essential for understanding its structure-function relationships, exploring its role in disease mechanisms, and assessing its potential as a therapeutic target. Overall, the synthesis and characterization of BEST3 recombinant proteins facilitate a deeper understanding of its biological functions and could eventually lead to novel interventions for related diseases.
