Analytical Data
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基因名
ITF1
- Application
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别名
TCF3; E2A; VDIR; Transcription Factor 3; E2A Immunoglobulin Enhancer Binding Factors E12/E47; Transcription Factor E2-alpha; VDR Interacting Repressor
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P15806
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表达区间
Ala421~Leu599
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分子量
30kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ITF1 (Immune Tolerance Factor 1) is a protein that plays a critical role in immune regulation and tolerance, making it a significant focus of research in immunology and therapeutic development. Understanding ITF1's function is essential for elucidating mechanisms underlying immune system disorders, such as autoimmune diseases and transplant rejection. Recent studies have indicated that ITF1 may influence immune cell differentiation and cytokine production, thereby shaping the immune response and preserving self-tolerance. The recombinant expression of ITF1 allows for detailed investigations into its structural and functional properties, enabling researchers to explore its potential as a biomarker for immune health and as a therapeutic target. Additionally, recombinant ITF1 can be used to develop novel immunotherapies aimed at modulating immune responses. As research progresses, the exploration of ITF1's interactions with other proteins and signaling pathways could provide further insights into its role in maintaining immune homeostasis and its implications in various diseases, paving the way for innovative treatment strategies.
