Analytical Data
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基因名
IPO9
- Application
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别名
Imp9; RANBP9; Ran-binding protein 9
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96P70
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表达区间
Val39~Glu213
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分子量
50kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The IPO9 protein, or Importin 9, is a member of the importin family involved in nucleocytoplasmic transport, playing a crucial role in the translocation of proteins between the nucleus and cytoplasm. The research surrounding IPO9 has gained momentum due to its significant implications in cellular processes such as cell growth, division, and response to cellular stress, which could influence various diseases, including cancer. Its role in the transport of diverse cargo proteins, including transcription factors and oncogenes, underscores its potential as a therapeutic target. Moreover, IPO9 has been implicated in the regulation of gene expression and cellular signaling pathways, making it an intriguing subject for investigating the molecular mechanisms underlying cellular homeostasis and pathogenesis. Understanding IPO9's structure, binding dynamics, and interactions with other cellular components is critical for deciphering its functions and exploring its applications in drug development and disease treatment. Consequently, the study of IPO9 and its recombinant protein provides vital insights into the intricate network of cellular transport mechanisms and holds promise for developing innovative therapeutic strategies aimed at diseases associated with dysregulated nucleocytoplasmic transport.
