Analytical Data
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基因名
OXCT1
- 应用
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别名
3 oxoacid CoA transferase 1; 3-oxoacid CoA-transferase 1; OXCT; Oxct1; SCOT; Scot S; Scot-S; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase (SCOT-s)
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种属
Human
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表达系统
E. coli
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标签
N-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P55809-1
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表达区间
T40-N520
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蛋白长度
Full Length of Isoform-1 Mature Protein
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分子量
61 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
OXCT1 (Oxoglutarate Carrier 1) is a crucial protein involved in mitochondrial metabolism, playing a significant role in the transport of oxoglutarate across the inner mitochondrial membrane. This protein is integral to the process of energy production, as it helps regulate the tricarboxylic acid (TCA) cycle and is involved in amino acid metabolism. Recent studies have highlighted OXCT1's potential implications in various metabolic disorders, including obesity, diabetes, and neurodegenerative diseases, thus making it a target of substantial interest in biomedical research. The need for a deeper understanding of OXCT1's structure and function has led to efforts in the expression and purification of recombinant OXCT1 protein. This allows researchers to investigate its biochemical properties, functional mechanisms, and interactions with other cellular components, paving the way for the development of potential therapeutic strategies aimed at modulating OXCT1 activity. By employing various molecular biology techniques, studies aim to elucidate the role of OXCT1 in health and disease, providing insights that could lead to novel treatment modalities for metabolic and neurodegenerative conditions.
