Cat: IPD-X38898

Recombinant Human MCM5 Protein,His

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Analytical Data

  • 基因名

    MCM5

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    CDC46; P1-CDC46; Cell Division Cycle 46; DNA replication licensing factor MCM5

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P33992

  • 表达区间

    Val331~Ile537

  • 分子量

    26kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

MCM5 (minichromosome maintenance 5) is a vital member of the MCM protein family, which plays a crucial role in DNA replication and the maintenance of genomic stability. As part of the MCM complex, MCM5 functions as a helicase, unwinding DNA strands during the replication process, thereby facilitating the accurate duplication of genetic material. Dysregulation of MCM5 expression has been implicated in various cancers, making it a potential biomarker and therapeutic target in oncology. Research on MCM5 recombinant proteins has gained traction, aiming to elucidate its molecular mechanisms and interactions within the cell cycle, particularly in the initiation of DNA replication. By using techniques such as recombinant DNA technology, scientists can produce MCM5 in a laboratory setting, allowing for detailed biochemical characterization and structural studies. Understanding how MCM5 operates within the MCM complex not only sheds light on fundamental cellular processes but also opens avenues for developing targeted therapies that inhibit its activity in cancerous cells. The exploration of MCM5’s role in DNA replication dynamics also raises important questions about its involvement in other cellular functions, potentially linking it to broader aspects of cell biology and disease. Overall, the research on MCM5 recombinant protein presents a promising field with significant implications for cancer therapy and our understanding of cell cycle regulation.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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