Analytical Data
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Gene name
DEFB130
- Application
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Alternative Names
Beta-defensin 30 Short name: DEFB-30 Defensin, beta 130
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Species
Human
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Source
Yeast
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q30KQ2
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Expression Region
23-79aa
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Molecular Weight
8.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DEFB130, also known as defensin beta 130, is a member of the defensin family of antimicrobial peptides, which play critical roles in the immune defense of various organisms. These peptides are primarily expressed in epithelial tissues and are known for their capacity to combat a broad spectrum of pathogens, including bacteria, viruses, and fungi. The study of DEFB130 reconstitution has gained interest due to its potential therapeutic implications in enhancing innate immune responses. Research has indicated that DEFB130 not only possesses antimicrobial properties but also modulates immune responses by influencing cell signaling pathways and inflammatory processes. Furthermore, genetic variations in the DEFB130 gene have been associated with various diseases, including autoimmune disorders and infections, highlighting its significance in human health. By producing recombinant DEFB130 protein, scientists aim to further elucidate its biological functions and mechanisms of action, paving the way for developing novel therapeutic strategies aimed at bolstering immune defense or treating immune-related diseases. Understanding the structure-function relationship of this defensin may also provide insights into its potential as a biomarker for disease susceptibility. Overall, the study of DEFB130 is of paramount importance in the fields of immunology and therapeutic development, as it holds promise for advancing our knowledge of host defense mechanisms and their applications in clinical settings.
