Analytical Data
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Gene name
OGC
- Application
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Alternative Names
OGCP; SLC25A11; SLC20A4; Solute Carrier Family 25 Member 11; Mitochondrial 2-oxoglutarate/malate carrier protein
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q02978
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Expression Region
Met1~Gly314
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Molecular Weight
38kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The research on OGC (Oxoglutarate Carrier) recombinant proteins has gained significant attention due to their critical role in cellular metabolism and mitochondrial function. OGC is responsible for the transport of oxoglutarate and other metabolites across the inner mitochondrial membrane, directly influencing the tricarboxylic acid (TCA) cycle and metabolic pathways related to energy production. Dysregulation of OGC activity has been implicated in various metabolic disorders and diseases, including cancer and neurodegenerative conditions. As a result, understanding the structure, function, and regulatory mechanisms of OGC is essential for elucidating its role in health and disease. The development of recombinant OGC proteins provides a powerful tool for studying their biochemical properties, interactions, and potential as therapeutic targets. By producing these proteins in a controlled laboratory setting, researchers can explore how OGCs contribute to mitochondrial dynamics and cellular homeostasis, paving the way for novel interventions in metabolic diseases and providing insights into the fundamental processes of cellular energy metabolism. Overall, the study of OGC recombinant proteins represents a promising frontier in metabolic research, with implications for both basic science and clinical applications.
