Analytical Data
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基因名
PCDHb10
- Application
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UN67
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表达区间
Thr64~Asp270
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分子量
27kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PCDHb10, or protocadherin beta 10, is a member of the protocadherin family, which plays a crucial role in neuronal development and synaptic functions. This protein is primarily expressed in the brain and is believed to be involved in cell-cell adhesion processes, influencing neuronal connectivity and potentially impacting various neurodevelopmental and neuropsychiatric disorders. Researchers have focused on the structure and function of PCDHb10 to understand its role in mediating neuronal assembly and maintaining synaptic integrity. Recent studies have indicated its importance in modulating calcium signaling and interacting with other synaptic proteins, making it a candidate of interest for investigating mechanisms underlying cognitive functions and deficits. The development of recombinant PCDHb10 protein is essential for biophysical studies, enabling researchers to explore its structural properties and interactions at a molecular level. Furthermore, understanding its function can lead to insights into the pathogenesis of diseases like autism spectrum disorders and schizophrenia, where alterations in synaptic dynamics are often observed. The ongoing research on PCDHb10 not only sheds light on its potential therapeutic implications but also enhances the understanding of complex neural networks in health and disease. Thus, unraveling the characteristics and mechanisms of PCDHb10 will facilitate the development of novel strategies for intervention in neurodevelopmental disorders.












