Analytical Data
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Gene name
NSMAF
- Application
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Alternative Names
FAN; Factor associated with neutral sphingomyelinase activation
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Species
Human
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q92636
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Expression Region
Arg176~Arg575
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Molecular Weight
77kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NSMAF, or non-specific immune modulator and antimicrobial factor, is a protein that has garnered attention in immunological and antimicrobial research due to its potential therapeutic applications. This protein is involved in the innate immune response, playing a crucial role in modulating the activity of immune cells and enhancing host defenses against pathogens. As antibiotic resistance continues to rise globally, the need for alternative antimicrobial strategies has become increasingly urgent. Recent studies have highlighted NSMAF's ability to stimulate immune responses and its potential to combat infections caused by resistant strains of bacteria and viruses. Research efforts have focused on the recombinant expression of NSMAF to produce sufficient quantities for detailed characterization and functional studies. This recombinant approach allows for the investigation of NSMAF’s structural properties, mechanisms of action, and interactions with various immune components. Understanding the role of NSMAF in immune modulation and antimicrobial activity could pave the way for the development of novel immunotherapeutics and antimicrobial agents, providing a valuable addition to existing treatment options in the fight against infectious diseases.
