Analytical Data
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基因名
INSM2
- Application
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别名
IA2; Mlt 1; Nbla106; Zinc finger protein IA-6
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96T92
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表达区间
Met1~Thr232
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分子量
54kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
INSM2 (Insulinoma-Associated Protein 2) is a transcription factor that plays a pivotal role in neuroendocrine differentiation and development, particularly in the context of neuroendocrine tumors. It is primarily expressed during embryogenesis and is associated with the regulation of insulin secretion and neuronal differentiation. Recent studies have highlighted the significance of INSM2 in the pathogenesis of various cancers, such as neuroblastoma and small cell lung cancer, where it serves as a potential biomarker for diagnosis and prognosis. The recombinant protein of INSM2 has gained attention in the research community for its potential applications in cancer therapy and diagnostics. By utilizing recombinant DNA technology, researchers can produce INSM2 protein in vitro, allowing for detailed analysis of its structural and functional properties. This research not only helps elucidate the molecular mechanisms by which INSM2 contributes to tumorigenesis but also paves the way for developing novel immunotherapeutic approaches targeting INSM2. Moreover, understanding the interactions of INSM2 with other signaling pathways can provide insights into its role in cellular processes such as proliferation, survival, and differentiation. As such, the characterization of recombinant INSM2 protein is fundamental to advancing our knowledge of neuroendocrine biology and improving therapeutic strategies for related malignancies.












