Analytical Data
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基因名
KIR2DS2
- Application
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别名
CD158J; Cl-49; Nkat5; 183ActI; CD158 antigen-like family member J; MHC class I NK cell receptor; Natural killer-associated transcript 5; NK receptor 183 ActI
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P43631
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表达区间
His22~Ala304
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分子量
60kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KIR2DS2 is a member of the Killer Immunoglobulin-like Receptor (KIR) family, which plays a crucial role in the immune system, particularly in the regulation of natural killer (NK) cell activity. Understanding the structure and function of KIR2DS2 is essential for elucidating its role in immune responses, especially in the context of viral infections and cancer. Research has shown that KIR2DS2 can recognize specific ligands on target cells, leading to NK cell activation and cytotoxic responses. The study of recombinant KIR2DS2 protein allows researchers to investigate its binding properties, signaling pathways, and functional interactions, providing insights into its mechanism of action. Furthermore, exploring the polymorphisms in the KIR gene cluster can help identify associations with various diseases, including autoimmune disorders and cancer susceptibility. Overall, the research on KIR2DS2 recombinant protein not only enhances our understanding of NK cell biology but also has potential therapeutic implications in designing immunotherapies and vaccines.
