Cat: IPD-X38743

Recombinant Human RGS8 Protein,His & GST

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Analytical Data

  • 基因名

    RGS8

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N- His & GST

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P57771

  • 表达区间

    Met1~Ser180

  • 分子量

    56kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

RGS8, or Regulator of G-protein Signaling 8, is a member of the RGS protein family, which plays a crucial role in regulating G-protein coupled receptor (GPCR) signaling. This family of proteins acts as molecular switches, enhancing the GTPase activity of G-alpha subunits, leading to the termination of signaling pathways activated by various external stimuli. The study of RGS8 has garnered attention due to its involvement in cardiovascular, neurological, and immune system functions, where dysregulation may lead to pathological conditions. Recent research efforts have focused on the structural and functional characterization of RGS8, including its interaction with different GPCRs and other signaling molecules. Understanding the specific interactions of recombinant RGS8 proteins is critical for unveiling their mechanisms in cellular signaling and may provide insights into therapeutic targets for diseases linked to GPCR dysfunction. Furthermore, the production of recombinant RGS8 proteins allows for in-depth studies using biochemical and biophysical techniques, which can elucidate the protein's role in signal transduction pathways. This research not only contributes to the fundamental understanding of G-protein signaling but also holds potential for the development of novel pharmacological strategies aimed at modulating RGS8 activity for therapeutic benefits. Overall, RGS8 represents a significant focus in the field of signal transduction research, with implications for both basic science and clinical applications.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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