Analytical Data
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Gene name
ABCG4
- Application
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Alternative Names
ABC-G4; WHITE2; ATP-Binding Cassette,Sub-Family G(WHITE)Member 4; Putative ABC Transporter
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H172
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Expression Region
Val59~Thr301
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Molecular Weight
31kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ABCG4 is a member of the ATP-binding cassette (ABC) transporter family, which plays a crucial role in the cellular transport of various lipid molecules, including cholesterol and phytosterols. This protein is particularly important in the context of lipid homeostasis and may influence cholesterol metabolism and related diseases. Research has shown that ABCG4 is expressed in various tissues, including the brain, where it is involved in the transport of lipids across the blood-brain barrier. Mutations or dysregulation of ABCG4 have been implicated in several metabolic disorders, including atherosclerosis and neurological conditions. Understanding the structure and function of ABCG4, particularly through the study of its recombinant protein, can provide insights into its specific roles in lipid transport and contribute to the development of potential therapeutic strategies for diseases linked to lipid dysregulation. Recent advances in recombinant protein technology have enabled researchers to produce and characterize ABCG4 more efficiently, paving the way for a deeper understanding of its physiological functions and mechanisms of action. Investigating ABCG4 not only enhances our knowledge of lipid biology but also offers potential pathways for drug discovery and the treatment of lipid-related disorders.
