Analytical Data
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基因名
ABCG4
- Application
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别名
ABC-G4; WHITE2; ATP-Binding Cassette,Sub-Family G(WHITE)Member 4; Putative ABC Transporter
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H172
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表达区间
Val59~Thr301
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分子量
31kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ABCG4 is a member of the ATP-binding cassette (ABC) transporter family, which plays a crucial role in the cellular transport of various lipid molecules, including cholesterol and phytosterols. This protein is particularly important in the context of lipid homeostasis and may influence cholesterol metabolism and related diseases. Research has shown that ABCG4 is expressed in various tissues, including the brain, where it is involved in the transport of lipids across the blood-brain barrier. Mutations or dysregulation of ABCG4 have been implicated in several metabolic disorders, including atherosclerosis and neurological conditions. Understanding the structure and function of ABCG4, particularly through the study of its recombinant protein, can provide insights into its specific roles in lipid transport and contribute to the development of potential therapeutic strategies for diseases linked to lipid dysregulation. Recent advances in recombinant protein technology have enabled researchers to produce and characterize ABCG4 more efficiently, paving the way for a deeper understanding of its physiological functions and mechanisms of action. Investigating ABCG4 not only enhances our knowledge of lipid biology but also offers potential pathways for drug discovery and the treatment of lipid-related disorders.
