Analytical Data
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基因名
PCI
- Application
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别名
SERPINA5; PAI3; PLANH3; PROCI; Serpin Peptidase Inhibitor Clade A 5; Plasma Serine Protease Inhibitor; Plasminogen Activator Inhibitor 3; Acrosomal serine protease inhibitor
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P05154
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表达区间
Ser43~Pro406
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分子量
45kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PCI (protein-conjugated immunotherapy) recombinant proteins have emerged as a pivotal focus in the field of immunotherapy, particularly in the context of cancer treatment. The human immune system is capable of targeting and eliminating cancer cells; however, tumors have developed various mechanisms to evade immune detection. Recombinant proteins, particularly those that are conjugated with tumor-associated antigens, can effectively enhance the immune response by presenting specific epitopes that stimulate T-cell activation and proliferation. This approach not only aids in educating the immune system to recognize and attack cancerous cells but also provides a targeted strategy to minimize damage to healthy tissues. Recent advances in genetic engineering and protein synthesis techniques have facilitated the design and production of these recombinant proteins, allowing for improved efficacy and safety profiles. Ongoing research explores various formulations, combination therapies, and delivery methods to optimize the immune response further. Moreover, the utilization of adjuvants in conjunction with PCI recombinant proteins aims to bolster immune activation and prolong the therapeutic effects. The burgeoning field of PCI recombinant proteins holds promise in establishing more effective cancer treatment modalities, paving the way for personalized medicine and improving clinical outcomes for patients suffering from malignancies. As this area of research evolves, it may offer significant insights into overcoming the limitations of traditional cancer therapies and contribute to the broader understanding of immune regulation in oncological contexts.












