Analytical Data
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Gene name
Avpr1a
- Application
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Alternative Names
AVPR V1aAntidiuretic hormone receptor 1aVascular/hepatic-type arginine vasopressin receptor
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Species
Rat
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P30560
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Expression Region
7-52aa
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Molecular Weight
31.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Avpr1a, or arginine vasopressin receptor 1A, is a G-protein coupled receptor that plays a crucial role in various physiological processes, including social behavior, stress response, and water homeostasis. Its significance in neuroscience and endocrinology has driven extensive research aimed at understanding its structure, function, and implications in human health. Dysfunction in the vasopressin system, particularly involving Avpr1a, has been implicated in several psychiatric disorders and conditions, such as social anxiety and autism spectrum disorders. The receptor is also linked to behaviors such as pair bonding and aggression, highlighting its importance in complex social interactions. To advance our understanding of Avpr1a, researchers have focused on characterizing its recombinant protein, enabling the study of its binding properties, signaling pathways, and interactions with ligands. This research is critical for developing potential therapeutic interventions targeting the Avpr1a receptor, which could provide new avenues for treating disorders related to social cognition and emotional regulation. Overall, the study of Avpr1a recombinant proteins stands at the intersection of molecular biology, pharmacology, and behavioral sciences, offering insights into the intricate connections between receptor activity and behavioral outcomes.
