Analytical Data
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Gene name
CA7
- Application
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Alternative Names
CA-VII; CAVII; Carbonate dehydratase VII
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9ERQ8
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Expression Region
Ser58~Pro217
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Molecular Weight
19kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CA7, or Carbonic Anhydrase 7, is a member of the carbonic anhydrase enzyme family, which plays a crucial role in regulating bicarbonate and proton concentrations in cells, thus influencing pH balance and ion transport. Research into CA7 has gained prominence due to its potential implications in physiological processes such as respiration, renal function, and bone resorption, as well as pathological conditions including cancer and metabolic disorders. The enzyme's expression patterns and function in different tissues have been subjects of investigation, revealing its involvement in various cellular mechanisms. For instance, altered levels of CA7 have been linked to specific types of tumors, providing insights into its role in tumorigenesis and metastasis. Additionally, the structural study of CA7 has highlighted its distinct active site, which could be targeted for drug design and therapeutic interventions. Understanding the functional dynamics of CA7 and its interactions at the molecular level continues to be a focus of research, aiming to elucidate its full biological significance and potential as a biomarker or therapeutic target in disease contexts. Through recombinant protein technology, CA7 can be produced in vitro, allowing for detailed biochemical assays and structural analysis, which are essential for uncovering its mechanisms of action and developing novel therapeutic strategies.
