Cat: IPD-X38618

Recombinant Human SPAG1 Protein,His

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Analytical Data

  • Gene name

    SPAG1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    HSD-3.8; SP75; TPIS

  • Species

    Human

  • Source

    E. coli

  • Tag

    N-His

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q07617

  • Expression Region

    Met1~Lys365

  • Molecular Weight

    46kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

SPAG1 (sperm-associated antigen 1) is a protein primarily expressed in the male reproductive system, particularly during spermatogenesis, playing a crucial role in sperm motility and fertility. Its significance has garnered attention in both reproductive biology and potential therapeutic developments. Research into SPAG1 is driven by the need to understand male infertility, which affects a substantial portion of the population, and the protein's involvement in sperm functionality provides a potential biomarker for male fertility assessment. Additionally, studies suggest SPAG1 may be implicated in various cellular processes, including cell signaling and motility, extending its relevance beyond reproduction. Investigating the recombinant form of SPAG1 allows researchers to explore its structural properties and functional mechanisms. This research aims to elucidate the role of SPAG1 in sperm development and assess its potential use in fertility treatments and diagnostic tools. Furthermore, understanding the interactions of SPAG1 with other proteins could provide insights into male reproductive health and lead to innovative approaches for addressing infertility issues. Overall, SPAG1 serves as an important focal point for advancing our knowledge of male fertility and developing prospective interventions to improve reproductive outcomes.

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