Analytical Data
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Gene name
SNTb1
- Application
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Alternative Names
SNT-B1; A1B; 59-DAP; BSYN2; DAPA1B; SNT2; SNT2B1; TIP43; Dystrophin-Associated Protein A1,59kDa,Basic Component 1; Syntrophin-2; Tax interaction protein 43
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q99L88
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Expression Region
Ala2~Gly297
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Molecular Weight
38kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SNTb1, a member of the SNT (Stargazin-like proteins) family, has gained attention in recent years due to its critical role in cellular signaling and synaptic function. This recombinant protein is predominantly expressed in the nervous system, where it participates in the regulation of neurotransmitter receptors, particularly AMPA and NMDA receptors. Research has indicated that SNTb1 is involved in synaptic plasticity, a fundamental process underlying learning and memory. Studies have also suggested that anomalies in SNTb1 function may contribute to neurodevelopmental disorders, making it a potential target for therapeutic intervention. The development of SNTb1 recombinant protein is crucial for detailed biochemical and biophysical studies, allowing researchers to investigate its structural properties and interaction dynamics with other proteins. Moreover, producing this protein in a recombinant form facilitates high-throughput screening for small molecules that can modulate its activity, thereby offering new avenues for drug discovery. The ongoing research on SNTb1 not only sheds light on its biological significance but also paves the way for understanding the molecular mechanisms of various neurological conditions, ultimately leading to improved treatment strategies.
