Analytical Data
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Gene name
EC 2.1.1.63
- Application
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Alternative Names
/
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Species
Human
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
B4DEE8
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Expression Region
4-238aa
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Molecular Weight
28.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
EC 2.1.1.63, known as S-adenosyl-L-methionine-dependent methyltransferase, plays a crucial role in various biological processes through its function in the methylation of diverse substrates. This enzyme is significant in the post-translational modification of proteins and nucleic acids, influencing gene expression and cellular signaling pathways. Research on EC 2.1.1.63 has gained momentum due to its implications in health and disease; alterations in its activity have been linked to several conditions, including cancer, cardiovascular diseases, and neurological disorders. Understanding the structure-function relationship of this enzyme can provide insights into its mechanism of action and potential therapeutic targets. Moreover, the exploration of EC 2.1.1.63's role in metabolic pathways highlights its importance in regulating cellular homeostasis and metabolic diseases. Advanced techniques, such as X-ray crystallography and molecular modeling, have enabled scientists to elucidate the enzyme's active sites and substrate interactions, paving the way for drug design and the development of potent inhibitors. As such, EC 2.1.1.63 continues to be a focal point of biochemical and pharmacological research, with the potential to yield significant advancements in medical science.
