Analytical Data
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Gene name
HIP1R
- Application
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Alternative Names
HIP12; HIP3; ILWEQ; Huntingtin Interacting Protein 12
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O75146
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Expression Region
Ser771~Ala1012
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Molecular Weight
30kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HIP1R, also known as Huntingtin Interacting Protein 1 Related, is a protein that has garnered significant interest within the realm of biomedical research due to its potential roles in various cellular processes and diseases. Initially identified for its interaction with Huntingtin, the protein associated with Huntington's disease, HIP1R is believed to play a crucial role in endocytosis and clathrin-mediated trafficking, thereby influencing cellular signaling pathways and membrane dynamics. Studies have indicated that alterations in HIP1R expression or function may be implicated in neurodegenerative diseases, cancer, and other pathological conditions. The investigation into HIP1R's structure, function, and interactions has the potential to unveil novel therapeutic targets and biomarkers. Recent advances in recombinant protein technology have enabled the production of purified HIP1R, allowing researchers to delve deeper into its molecular mechanisms and biological significance. Understanding HIP1R's role could provide insights into its contributions to cell survival and death, highlighting its importance in maintaining cellular homeostasis. Thus, research on recombinant HIP1R not only enhances our understanding of fundamental biological processes but also paves the way for innovative strategies to combat diseases associated with its dysfunction.
