Analytical Data
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基因名
DBN1
- Application
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别名
Developmentally-regulated brain protein
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q16643
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表达区间
Gly3~Ser134
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分子量
19kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DBN1, or Dynamin Binding Protein 1, is an important protein implicated in various cellular processes, particularly in the context of neurobiology. Research into DBN1 has gained momentum due to its potential role in synaptic function, neuronal development, and its association with several neurological disorders. The protein is known to interact with dynamin, a GTPase crucial for membrane fission during endocytosis, and plays a significant role in the regulation of synaptic vesicle trafficking. Dysregulation of DBN1 expression or function has been linked to diseases such as schizophrenia, autism spectrum disorders, and other neurodevelopmental conditions. Recent advances in molecular biology techniques have enabled deeper investigations into the mechanisms underlying DBN1's role in neurons, including the exploration of post-translational modifications and protein-protein interactions. Additionally, the development of recombinant DBN1 proteins allows for in vitro studies to elucidate its functional properties, potential binding partners, and pathophysiological relevance. Understanding DBN1's role may provide insights into the molecular basis of synaptic dysfunction in various neurodevelopmental disorders and open avenues for targeted therapeutic strategies.
