Analytical Data
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基因名
CTBP1
- Application
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别名
BARS; Brefeldin A-Ribosylated Substrate
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q13363
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表达区间
Met1~Phe250
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分子量
31kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CTBP1 (C-terminal binding protein 1) is a significant transcriptional co-regulator implicated in various cellular processes, including cell differentiation, proliferation, and apoptosis. It functions as a transcriptional repressor by interacting with a variety of transcription factors and chromatin-modifying complexes. Dysregulation of CTBP1 has been associated with several malignancies, making it a potential target for cancer therapy. Additionally, CTBP1 plays a critical role in embryonic development and has been linked to several congenital disorders. Given its multifaceted roles in cellular and developmental biology, there is a growing interest in characterizing CTBP1 through recombinant protein studies. Research has focused on elucidating its structure-function relationship, understanding its protein-protein interactions, and exploring its downstream effects on gene expression. Recombinant CTBP1 protein can be utilized in various biochemical assays to investigate its role in transcriptional regulation and to screen for small-molecule inhibitors that may block its oncogenic activities. Overall, the study of CTBP1 recombinant protein is essential for understanding its biological functionality and therapeutic potential in cancer and other diseases.
