Analytical Data
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基因名
CEP110
- Application
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别名
FAN; CP110; CEP1; Centriolin; Centrosomal Protein 1
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q7Z7A1
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表达区间
Ile2101~Arg2325
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分子量
34kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CEP110 is a key protein that plays a critical role in the regulation of ciliogenesis and the maintenance of centrosomal structure. As a centrosomal protein, CEP110 is involved in the assembly and function of centrioles, which are essential for proper cell division and the formation of cilia. Abnormalities in CEP110 expression and function have been linked to various ciliopathies and cancer, highlighting its significance in cellular processes. Recent studies have demonstrated that CEP110 interacts with other essential proteins involved in cell cycle regulation and ciliogenesis, suggesting its multifaceted role in cellular dynamics. The recombinant expression of CEP110 provides a valuable tool for elucidating its function and interactions, allowing researchers to investigate its mechanistic roles in normal and pathological contexts. Overall, understanding the biochemical properties and functions of CEP110 through recombinant protein studies could pave the way for novel therapeutic strategies in diseases associated with centrosomal dysfunction.
