Analytical Data
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Gene name
BDKRB2
- Application
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Alternative Names
BDKR-B2; B2R; BK2; BKR2; BRB2
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Species
Human
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P30411
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Expression Region
Met1~Gln60
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Molecular Weight
38kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BDKRB2, or Bradykinin B2 receptor, plays a pivotal role in various physiological processes, including vasodilation, inflammation, and pain signaling. It is a G-protein-coupled receptor that is activated by bradykinin, a potent peptide involved in inflammatory responses. Research on BDKRB2 and its recombinant protein has gained momentum due to its implications in several pathological conditions, such as cardiovascular diseases, asthma, and chronic pain syndromes. Understanding the molecular mechanisms and pathways associated with BDKRB2 activation can lead to the development of novel therapeutic strategies. The recombinant protein serves as a valuable tool to study receptor functionality, ligand interactions, and downstream signaling cascades. Additionally, BDKRB2 is a potential target for drug discovery, as modulating its activity could offer new avenues for treating diseases characterized by excessive inflammation or pain. With advancements in biotechnology, researchers are now able to produce high-quality BDKRB2 recombinant proteins, facilitating detailed biochemical and pharmacological studies that contribute to a deeper understanding of its role in human health and disease.
