Analytical Data
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基因名
PSPN
- Application
-
别名
PSP
-
种属
Human
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表达系统
E. coli
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标签
N- His & GST
-
纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O60542
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表达区间
Val29~Gly156
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分子量
44kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PSPN (Proteolipid Protein 1), a critical component of myelin in the central nervous system, has garnered significant interest in research due to its key role in the formation and maintenance of myelin sheaths. Myelin sheaths are essential for the proper functioning of neuronal communication, as they facilitate the rapid transmission of electrical impulses along axons. Disruptions in myelin integrity are implicated in various neurological disorders, including multiple sclerosis and leukodystrophies. Recent studies have focused on the biochemical and structural characterization of PSPN to better understand its functions and interactions within myelin. Advancements in techniques such as cryo-electron microscopy and X-ray crystallography have allowed researchers to elucidate the molecular organization of PSPN and its impact on myelin stability. Additionally, studies investigating the mutations in the PSPN gene have provided insights into how alterations in its expression and function may lead to demyelination and neurological deficits. Understanding the role of PSPN not only aids in comprehending myelination processes but also paves the way for potential therapeutic strategies aimed at repairing myelin damage and treating related diseases. As the field progresses, the ongoing exploration of PSPN could unveil novel pathways for intervention and enhance our understanding of myelin-associated disorders.












