Analytical Data
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基因名
COL13
- Application
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别名
COL13A1; COL13-A1; Collagen Alpha-1(XIII)chain
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5TAT6
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表达区间
Met443~Lys717
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分子量
34kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
COL13, or collagen type XIII, is a fibril-associated collagen primarily located in the extracellular matrix (ECM) of various tissues, playing a crucial role in cell adhesion, migration, and tissue integrity. Its unique structure, characterized by a short triple-helical domain and several non-collagenous segments, facilitates diverse interactions with other ECM components and cell surface receptors. Research into COL13 has gained momentum due to its potential implications in various pathological conditions, including cancers, fibrotic diseases, and cardiovascular disorders. Studies have shown that COL13 may influence tumor progression and metastasis, highlighting its role as a potential biomarker and therapeutic target in oncology. Furthermore, due to its involvement in fibrotic processes, understanding COL13's function could lead to new strategies for treating chronic tissue injuries and organ fibrosis. Recent advances in recombinant protein technology have enabled the production of COL13 in recombinant form, allowing for more straightforward investigation of its structure-function relationships and biological activities. This has facilitated the exploration of its potential applications in tissue engineering and regenerative medicine, where COL13 could be harnessed to improve scaffold materials for enhancing cellular behavior and promoting tissue regeneration. Overall, COL13's multifaceted roles in health and disease underscore the importance of continued research into its biochemical properties and therapeutic potential.
