Analytical Data
-
Gene name
GLUT2
- Application
-
Alternative Names
SLC2A2; SLC2-A2; Solute carrier family 2, facilitated glucose transporter member 2; Glucose transporter type 2, liver
-
Species
Human
-
Source
E. coli
-
Tag
N- His & GST
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P11168
-
Expression Region
Cys239~Pro303
-
Molecular Weight
42kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GLUT2, or glucose transporter type 2, is a crucial protein involved in glucose metabolism and homeostasis, primarily expressed in the liver, pancreas, and intestines. It facilitates the transport of glucose across cell membranes, playing a vital role in regulating blood sugar levels and influencing insulin secretion. Given its significance in metabolic disorders such as diabetes, understanding GLUT2's structure and function is pivotal for developing therapeutic strategies. Recombinant GLUT2 proteins are utilized in research to dissect the transport mechanisms and to explore the effects of various ligands and inhibitors on its activity. The production of GLUT2 in a recombinant form allows researchers to study its properties in controlled environments, enabling investigations into its role in glucose sensing and insulin response. Additionally, identifying post-translational modifications and interaction partners of GLUT2 can provide insights into its regulatory mechanisms. This research is essential as it not only enhances our understanding of GLUT2's physiological roles but also contributes to the broader field of metabolic disease research, where targeting GLUT2 could lead to innovative treatments for conditions such as type 2 diabetes and obesity. The insights gained from studies involving recombinant GLUT2 proteins offer the potential to uncover novel biomarkers and therapeutic targets, ultimately aiming to improve metabolic health outcomes.
