Analytical Data
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基因名
GLUT2
- Application
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别名
SLC2A2; SLC2-A2; Solute carrier family 2, facilitated glucose transporter member 2; Glucose transporter type 2, liver
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P11168
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表达区间
Cys239~Pro303
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分子量
42kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GLUT2, or glucose transporter type 2, is a crucial protein involved in glucose metabolism and homeostasis, primarily expressed in the liver, pancreas, and intestines. It facilitates the transport of glucose across cell membranes, playing a vital role in regulating blood sugar levels and influencing insulin secretion. Given its significance in metabolic disorders such as diabetes, understanding GLUT2's structure and function is pivotal for developing therapeutic strategies. Recombinant GLUT2 proteins are utilized in research to dissect the transport mechanisms and to explore the effects of various ligands and inhibitors on its activity. The production of GLUT2 in a recombinant form allows researchers to study its properties in controlled environments, enabling investigations into its role in glucose sensing and insulin response. Additionally, identifying post-translational modifications and interaction partners of GLUT2 can provide insights into its regulatory mechanisms. This research is essential as it not only enhances our understanding of GLUT2's physiological roles but also contributes to the broader field of metabolic disease research, where targeting GLUT2 could lead to innovative treatments for conditions such as type 2 diabetes and obesity. The insights gained from studies involving recombinant GLUT2 proteins offer the potential to uncover novel biomarkers and therapeutic targets, ultimately aiming to improve metabolic health outcomes.
