Analytical Data
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Gene name
HAT1
- Application
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Alternative Names
KAT1; Histone acetyltransferase type B catalytic subunit
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8BY71
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Expression Region
Glu100~Asp338
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Molecular Weight
30kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HAT1 (Histone Acetyltransferase 1) is an important enzyme involved in the acetylation of histone proteins, which plays a crucial role in the regulation of gene expression and chromatin dynamics. The study of HAT1 has gained significant attention due to its implications in various biological processes, including cell proliferation, differentiation, and apoptosis. Moreover, dysregulation of HAT1 has been implicated in several diseases, including cancer, where altered histone acetylation patterns can lead to aberrant gene expression profiles. Researchers have focused on characterizing the enzymatic activity of HAT1, its substrate specificity, and the molecular mechanisms by which it influences chromatin structure and function. Recombinant HAT1 protein has been produced for in vitro studies, enabling the exploration of its role in histone modification in greater detail. Understanding the structure-function relationships of HAT1, as well as its interactions with other cofactors and regulatory proteins, is essential for elucidating its function in health and disease. This knowledge could pave the way for the development of targeted therapeutic strategies aimed at modulating HAT1 activity to restore normal gene expression patterns in pathological conditions.
