Analytical Data
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Gene name
CTSS
- Application
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Alternative Names
CTS-S
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O70370
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Expression Region
Leu123~Glu339
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Molecular Weight
33kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CTSS (Cathepsin S) is a cysteine protease that plays a significant role in various physiological and pathological processes, including immune response, inflammation, and cancer progression. As a member of the cathepsin family, CTSS is predominantly expressed in antigen-presenting cells and is crucial for the processing of major histocompatibility complex (MHC) class II molecules, thus influencing T-cell activation. Research has shown that aberrant CTSS activity is linked to several diseases, including autoimmune disorders and tumors, making it a potential therapeutic target. The recombinant production of CTSS has enabled scientists to study its function and to explore its role in disease mechanisms in more detail. By generating CTSS in a controlled laboratory setting, researchers can investigate its enzymatic properties, interactions with substrates, and regulatory mechanisms. Additionally, the availability of recombinant CTSS facilitates the development of inhibitors that could be useful in clinical settings, including cancer therapeutics and immunomodulation. The ongoing studies aim not only to clarify CTSS's biological functions but also to harness its potential in designing novel treatment strategies targeting various disease pathways.
