Analytical Data
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Gene name
FZD9
- Application
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Alternative Names
CD349; FZD3
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O00144
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Expression Region
Leu23~Asp229
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Molecular Weight
30kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FZD9, or Frizzled-9, is a member of the Frizzled family of G protein-coupled receptors that play a significant role in the Wnt signaling pathway, which is crucial for various biological processes including embryonic development, tissue homeostasis, and stem cell regulation. Abnormalities in Wnt signaling have been implicated in numerous diseases, including cancer, neurodegenerative disorders, and cardiac diseases, making FZD9 a potential target for therapeutic interventions. The study of recombinant FZD9 proteins has gained traction as researchers aim to elucidate its structure, function, and interactions with Wnt ligands and other signaling molecules. By producing recombinant FZD9 proteins, scientists can perform functional assays to better understand how FZD9 mediates signaling transduction and its role in regulating gene expression. Furthermore, engineered FZD9 proteins can serve as valuable tools for drug discovery, enabling the identification of small molecules or peptides that modulate its activity. Overall, the research on recombinant FZD9 proteins not only enhances our understanding of the fundamental biology of Wnt signaling but also opens avenues for novel therapeutic strategies in diseases associated with its dysregulation.
