Analytical Data
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基因名
SGK1
- Application
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别名
Serine/threonine-protein kinase Sgk1
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9WVC6
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表达区间
Ser145~Asp386
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分子量
30kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SGK1 (serum/glucocorticoid-regulated kinase 1) is a serine/threonine kinase that plays a crucial role in various cellular processes, including cell survival, proliferation, and stress response. It is a member of the AGC (PKA, PKG, and PKC) kinase family and is known to be involved in the signaling pathways activated by growth factors and hormones. Since SGK1 is implicated in numerous physiological and pathological conditions, such as cancer, obesity, and cardiovascular diseases, researchers have focused on understanding its molecular mechanisms and functional roles. The recombinant expression of SGK1 protein has gained attention as it enables detailed studies of its biochemical properties, substrate specificity, and interactions with other signaling molecules. By producing SGK1 as a recombinant protein, scientists can investigate its enzymatic activity, identify potential inhibitors, and characterize its structural features using techniques like X-ray crystallography and NMR spectroscopy. Furthermore, studying SGK1 in a recombinant form allows for the exploration of its therapeutic potential in diseases where its dysregulation is a factor. Overall, SGK1 recombinant protein research is significant for uncovering new insights into cellular signaling mechanisms and developing targeted therapies for diseases associated with aberrant SGK1 activity.












