Analytical Data
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Gene name
KLF5
- Application
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Alternative Names
KLF5; BTEB2; CKLF; IKLF; Intestinal Enriched Krüppel-Like Factor; Colon krueppel-like factor; Basic Transcription Element Binding Protein 2; GC-box-binding protein 2
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Species
Human
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Source
E. coli
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Tag
N-6His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13887
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Expression Region
216~457aa
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Molecular Weight
31kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Identification
Protein Description
KLF5, a member of the Kruppel-like factor family, is a transcription factor that plays a crucial role in regulating various biological processes, including cell proliferation, differentiation, and apoptosis. Its involvement in several diseases, particularly cancer, has garnered significant interest from researchers. Studies have shown that KLF5 is overexpressed in various types of tumors, contributing to tumorigenesis by promoting cell cycle progression and inhibiting apoptosis. The ability to manipulate KLF5 activity offers promising therapeutic avenues for cancer treatment. To better understand its functional mechanisms and develop targeted therapies, researchers have increasingly turned to the generation of recombinant KLF5 proteins. These proteins can be used in biochemical assays and cell-based studies to elucidate KLF5's role in transcriptional regulation and its interactions with other cellular molecules. Additionally, recombinant KLF5 serves as a valuable tool for investigating its potential as a biomarker for cancer progression and response to therapy. Overall, the study of KLF5 recombinant proteins provides vital insights into the molecular underpinnings of disease and paves the way for innovative therapeutic strategies.
