Analytical Data
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基因名
MRPL11
- Application
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别名
MRPL11; CGI-113; 39S ribosomal protein L11; mitochondrial; L11mt; MRP-L11; Mitochondrial large ribosomal subunit protein uL11m
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y3B7
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表达区间
1-191aa
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分子量
36.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MRPL11, a mitochondrial ribosomal protein, plays a crucial role in mitochondrial protein synthesis and cellular energy metabolism. It is part of the mitochondrial ribosome, which is essential for translating mitochondrial DNA-encoded proteins that are vital for oxidative phosphorylation and ATP production. Recent studies have highlighted the importance of MRPL11 in various biological processes, including cell proliferation, apoptosis, and response to stress. Abnormal expressions of MRPL11 have been associated with several diseases, including cancer and mitochondrial disorders, underscoring its potential as a biomarker and therapeutic target. Moreover, understanding the structure and function of MRPL11 is essential for unraveling the complexities of mitochondrial functions and their implications in health and disease. As such, recombinant MRPL11 is being investigated for its potential applications in research and medicine, including studies on mitochondrial dysfunctions and the development of novel therapeutic approaches. The elucidation of MRPL11's interactions with other mitochondrial components and its regulatory mechanisms is anticipated to enhance our understanding of mitochondrial biogenesis, dynamics, and disease pathology.
