Analytical Data
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基因名
GDI1
- Application
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别名
GDIL; MRX41; MRX48; OPHN2; RABGD1A; RABGDIA; XAP-4; Guanine Nucleotide Dissociation Inhibitor; Rab GDP Dissociation Inhibitor Alpha 1; Oligophrenin-2
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P31150
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表达区间
Met1~Val274
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分子量
35kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GDI1 (GDP dissociation inhibitor 1) is a crucial regulatory protein that plays a significant role in the control of the small GTPases, particularly the Ras and Rab families. These GTPases are vital for various cellular processes, including signal transduction, vesicle trafficking, and cell proliferation. Dysregulation of GDI1 and its associated pathways has been implicated in several diseases, including cancer and neurodegenerative disorders. Research on the recombinant GDI1 protein has gained momentum due to its potential therapeutic applications and the need to understand its functional mechanisms at a molecular level. Producing GDI1 as a recombinant protein allows for the detailed analysis of its structure, interactions with GTPases, and its effects in cellular contexts. Advances in recombinant protein technology have enabled the efficient expression and purification of GDI1, facilitating studies that explore its biochemical properties and regulatory functions. Investigating the role of GDI1 in cellular pathways not only enhances our understanding of GTPase-mediated signaling but also opens avenues for targeted therapeutic strategies that could address the consequences of GDI1 malfunction. As such, the study of recombinant GDI1 protein is a vital aspect of ongoing research efforts aiming to elucidate its role in cellular dynamics and its potential as a therapeutic target.
