Analytical Data
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Gene name
A2BP1
- Application
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Alternative Names
RBFOX1; FOX1; HRNBP1; A2-BP1; Hexaribonucleotide Binding Protein 1; RNA Binding Protein,Fox-1 Homolog 1
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Species
Rat
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
D3ZSL1
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Expression Region
Asp149~Ser399
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Molecular Weight
32kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
A2BP1, or Ataxin-2-binding protein 1, is a member of the RNA-binding protein family that plays a crucial role in post-transcriptional regulation of gene expression. Research into A2BP1 has gained momentum due to its implications in various neurological disorders and developmental processes. Its involvement in key cellular functions, such as mRNA splicing, stability, and transport, underscores its significance in the nervous system, where it influences neuronal differentiation and synaptic function. Mutations and dysregulation of A2BP1 have been linked to diseases, including autism spectrum disorders and other neurodevelopmental conditions, indicating its potential as a therapeutic target. Recent studies have focused on understanding the structural properties and molecular mechanisms of A2BP1, shedding light on its interactions with RNA and other proteins. Investigating A2BP1's functional roles in neuronal context and its pathways could unveil new insights into its contribution to brain development and disease, positioning it as a key player in both basic neuroscience research and clinical applications.
