Cat: IPD-X38383

Recombinant Human GTF2E1 Protein,His

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Analytical Data

  • 基因名

    GTF2E1

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    TFIIE-A; FE; TFIIE; TF2E1; TF2-E1; Transcription Factor II E1; General transcription factor IIE 56 kDa subunit; Transcription initiation factor IIE subunit alpha

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P29083

  • 表达区间

    Lys15~Gln306

  • 分子量

    40kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

GTF2E1, or General Transcription Factor II E1, is a vital component of the transcription machinery in eukaryotic cells, playing a crucial role in the initiation of transcription by RNA polymerase II. This protein is part of a multi-subunit complex that facilitates the assembly of the transcription pre-initiation complex, which is essential for the accurate and efficient transcription of protein-coding genes. Research on recombinant GTF2E1 has garnered considerable attention as it helps elucidate the mechanisms underlying gene regulation and expression. Understanding the structure and function of GTF2E1 can provide insights into its interactions with other transcription factors and regulatory elements, which may have implications in various cellular processes and disease states, including cancer. Moreover, the production of recombinant GTF2E1 offers opportunities for biochemical assays and structural studies, enabling researchers to analyze its function at a molecular level. Investigations into the post-translational modifications of GTF2E1 can further reveal its regulatory roles and potential as a therapeutic target. Given the importance of transcriptional regulation in cellular homeostasis, the study of GTF2E1 not only enhances our fundamental knowledge of gene expression but also paves the way for potential interventions in pathological conditions where transcriptional dysregulation occurs.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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