Analytical Data
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Gene name
MUC6
- Application
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Alternative Names
Mucin 6,Gastric; Oligomeric Mucus/Gel-Forming
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Species
Human
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6W4X9
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Expression Region
Leu2338~Asp2439
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Molecular Weight
41kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MUC6 is a member of the mucin gene family, which encodes glycoproteins that play crucial roles in protecting epithelial surfaces and maintaining mucosal integrity. It is predominantly expressed in the gastric mucosa and is implicated in various physiological processes, including lubrication, barrier function, and modulation of immune responses. Research into MUC6 is particularly significant due to its involvement in gastrointestinal diseases, such as gastric cancer and chronic gastritis, where its expression patterns may serve as potential biomarkers for disease progression. The recombinant form of MUC6 has gained attention in the context of developing therapeutic strategies and diagnostic tools. By producing recombinant MUC6 protein, researchers aim to better understand its structure-function relationships, interactions with other biomolecules, and its role in cell signaling pathways. Additionally, recombinant MUC6 can be utilized in vaccine development and as an adjuvant in immunotherapy, given its potential to enhance immune responses. Ongoing studies focus on characterizing the immunogenic properties of MUC6 and its applications in medical research. Overall, the exploration of recombinant MUC6 offers valuable insights into its biological significance and potential therapeutic applications, contributing to advancements in the understanding and treatment of related diseases.
