Analytical Data
-
Gene name
EBF2
- Application
-
Alternative Names
COE2; Transcription factor COE2
-
Species
Human
-
Source
E. coli
-
Tag
N-His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9HAK2
-
Expression Region
Val285~Val536
-
Molecular Weight
31kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
EBF2 (Early B-cell Factor 2) is a transcription factor that plays a crucial role in B-cell development and immune response regulation. It is part of the EBF family of proteins, which are essential for the differentiation of B lymphocytes, influencing processes such as gene expression and cell signaling pathways. Research on EBF2 has gained traction due to its involvement in hematopoiesis and its potential link to various immune disorders and cancers. Recent studies have indicated that EBF2 not only regulates B-cell lineage commitment but also impacts the maintenance of immune homeostasis. Given the increasing prevalence of autoimmune diseases and malignancies associated with immune system dysregulation, understanding the molecular mechanisms underlying EBF2 function is of significant interest. Additionally, EBF2's role in promoting the maturation of B cells into antibody-producing plasma cells has made it a target for therapeutic strategies aimed at enhancing vaccine responses or treating immunodeficiencies. As researchers continue to explore the structure-function relationship of EBF2 through recombinant protein studies, insights gained from these investigations hold promise for novel interventions in immunotherapy and regenerative medicine. The development of recombinant EBF2 proteins allows for the detailed examination of its biochemical properties and interactions with other cellular factors, which is crucial for decoding its role in immune regulation and potential applications in clinical settings.
