Cat: IPD-X38373

Recombinant Human EBF2 Protein,His

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Analytical Data

  • 基因名

    EBF2

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    COE2; Transcription factor COE2

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9HAK2

  • 表达区间

    Val285~Val536

  • 分子量

    31kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

EBF2 (Early B-cell Factor 2) is a transcription factor that plays a crucial role in B-cell development and immune response regulation. It is part of the EBF family of proteins, which are essential for the differentiation of B lymphocytes, influencing processes such as gene expression and cell signaling pathways. Research on EBF2 has gained traction due to its involvement in hematopoiesis and its potential link to various immune disorders and cancers. Recent studies have indicated that EBF2 not only regulates B-cell lineage commitment but also impacts the maintenance of immune homeostasis. Given the increasing prevalence of autoimmune diseases and malignancies associated with immune system dysregulation, understanding the molecular mechanisms underlying EBF2 function is of significant interest. Additionally, EBF2's role in promoting the maturation of B cells into antibody-producing plasma cells has made it a target for therapeutic strategies aimed at enhancing vaccine responses or treating immunodeficiencies. As researchers continue to explore the structure-function relationship of EBF2 through recombinant protein studies, insights gained from these investigations hold promise for novel interventions in immunotherapy and regenerative medicine. The development of recombinant EBF2 proteins allows for the detailed examination of its biochemical properties and interactions with other cellular factors, which is crucial for decoding its role in immune regulation and potential applications in clinical settings.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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