Recombinant Human NUP188 Protein，His & GST

NUP188, a member of the nucleoporin family, is an integral component of the nuclear pore complex (NPC) that plays a crucial role in nucleocytoplasmic transport, facilitating the movement of proteins and RNA across the nuclear envelope. Recent studies have highlighted the importance of NUP188 in various cellular processes, including gene expression regulation, cell signaling, and maintaining nuclear integrity. Dysregulation of NUP188 has been implicated in several diseases, notably cancers, where alterations in nucleocytoplasmic transport mechanisms can lead to aberrant cell proliferation and survival. The study of recombinant NUP188 protein presents an opportunity to better understand its structural and functional properties, including its interactions with other nucleoporins and its role in the assembly of the NPC. By producing and characterizing recombinant NUP188, researchers aim to elucidate its specific contributions to nucleocytoplasmic transport and identify potential therapeutic targets for diseases associated with its dysregulation. This research is particularly relevant given the growing recognition of the nuclear pore complex as a pivotal player in cell biology and disease pathology, making NUP188 a promising candidate for further investigation in the context of cellular transport mechanisms and oncogenesis.