Analytical Data
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基因名
GLUT3
- Application
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别名
SLC2A3; Solute Carrier Family 2(Facilitated Glucose Transporter)Member 3; Glucose transporter type 3, brain
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种属
Rat
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
Q07647
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表达区间
Cys205~Pro269
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分子量
28kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GLUT3, or Glucose Transporter Type 3, is a key protein responsible for the transport of glucose across the plasma membrane of cells, particularly in the brain and other tissues that are highly dependent on glucose for energy. Its role is critical in maintaining glucose homeostasis and supporting cellular metabolism. Research indicates that GLUT3 plays a significant role in neurodegenerative diseases, obesity, and cancer, making it a potential target for therapeutic interventions. Due to its high affinity for glucose, GLUT3 is crucial for neurons, which require a constant supply of glucose to function effectively. The recombinant expression of GLUT3 as a protein allows for detailed studies into its structure, function, and regulation. By producing GLUT3 through recombinant DNA technology, researchers can explore its transport mechanisms, analyze how it binds to glucose, and investigate the effects of various ligands or inhibitors. Understanding the biophysical properties of GLUT3 can provide insights into its role in health and disease, paving the way for the development of novel treatments for metabolic disorders and brain-related conditions. Thus, the research surrounding GLUT3 recombinant protein is vital for advancing our comprehension of glucose transport physiology and its implications in various pathological states.
