Analytical Data
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基因名
PTPRK
- Application
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别名
R-PTP-Kappa; PTPR-K; Protein-tyrosine phosphatase kappa
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15262
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表达区间
Thr1185~Ser1440
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分子量
33kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PTPRK, or Protein Tyrosine Phosphatase Receptor Type K, is a key enzyme involved in the regulation of various cellular processes, including cell proliferation, differentiation, and signaling pathways. Its role in dephosphorylating tyrosine residues on proteins makes it crucial for maintaining cellular homeostasis and responding to extracellular stimuli. Research has increasingly focused on PTPRK due to its implications in various diseases, particularly cancer, where dysregulation of tyrosine phosphorylation is a common feature. Studies have shown that PTPRK can act as a tumor suppressor in certain contexts, implicating its potential as a therapeutic target. Given the complexity of protein interactions and the need for precise regulation of signaling pathways, recombinant PTPRK proteins offer a valuable tool for elucidating its biological functions and mechanisms. By producing PTPRK in a recombinant system, researchers can obtain substantial quantities of the protein for extensive biochemical analyses and functional assays, thereby enhancing our understanding of its role in cellular signaling and disease pathology. This advancing research on PTPRK not only furthers our understanding of signal transduction mechanisms but also holds promise for the development of novel therapeutic strategies in cancer and other conditions associated with aberrant tyrosine phosphorylation.
