Analytical Data
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基因名
CXCL1
- Application
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别名
NAP3; GRO1; GROa; GRO-A; MGSA-A; NAP3; SCYB1; Chemokine C-X-C-Motif Ligand 1; Melanoma Growth Stimulating Activity Alpha; Fibroblast Secretory Protein
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P12850
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表达区间
Ala25~Lys96
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分子量
12kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CXCL1, also known as Gro-α (Growth-regulated oncogene), is a chemokine that plays a crucial role in immune response, inflammation, and tissue repair. It is primarily produced by various types of cells, including macrophages, fibroblasts, and endothelial cells, in response to pro-inflammatory stimuli. CXCL1 is involved in the recruitment of neutrophils to sites of infection and injury, facilitating the resolution of inflammation. Given its important role in inflammatory diseases, cancer progression, and wound healing, CXCL1 has garnered significant attention in biomedical research. The recombinant form of CXCL1 is engineered to study its functional characteristics, therapeutic potential, and mechanistic pathways in various pathological conditions. Researchers utilize recombinant CXCL1 to explore its effects on immune cell behavior, angiogenesis, and tumor microenvironment interactions. Understanding the structure-function relationship and signaling pathways of CXCL1 may lead to new therapeutic strategies aimed at modulating its activity in disease contexts, such as chronic inflammatory disorders and cancer. Overall, the study of recombinant CXCL1 provides insights into its biological significance and potential clinical applications in enhancing tissue repair and treating inflammatory diseases.
