Cat: IPD-X38216

Recombinant Human LASS2 Protein(HEK293),His

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Analytical Data

  • 基因名

    LASS2

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    SP260; L3; TMSG1; CerS2; Longevity Assurance(LAG1)Homolog 2; Ceramide Synthase 2; LAG1 Longevity Assurance Homolog 2; Tumor Metastasis Suppressor Gene 1 Protein

  • 种属

    Human

  • 表达系统

    HEK293

  • 标签

    N- His & C- Fc Region of Human IgG1

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q96G23

  • 表达区间

    Arg325~Asp380

  • 分子量

    38kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

LASS2, or "Lipid-associated synthase 2," is a member of the LASS family, which plays a significant role in the biosynthesis of sphingolipids, critical components of cellular membranes that influence various biological processes. Research into LASS2 has gained momentum due to its potential implications in cancer biology and neurodegenerative diseases, where altered sphingolipid metabolism can contribute to disease progression. Initial studies suggested that LASS2 is involved in regulating apoptosis and cellular signaling pathways by modulating sphingolipid levels. Furthermore, its expression patterns are often altered in various cancer types, indicating its potential as a biomarker for tumor progression and as a therapeutic target. The recombinant expression of LASS2 permits detailed studies on its enzymatic properties and interactions with other cellular components, thereby enhancing our understanding of its biological functions. In light of its role in critical physiological and pathological processes, the investigation of LASS2 as a recombinant protein not only contributes to basic science but also holds promise for developing novel therapeutic strategies aimed at manipulating sphingolipid metabolism in disease contexts. Thus, ongoing research seeks to elucidate the precise mechanisms by which LASS2 operates and its influence on cellular homeostasis and disease states, paving the way for potential clinical applications.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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