Analytical Data
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Gene name
SLITRK6
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简介
The SLITRK6 protein is a key regulator that coordinates neurite growth, which is critical for normal hearing and vision, affecting neuronal development and intercellular communication. Its importance in sensory function emphasizes its important role in the molecular mechanisms of sensory perception. SLITRK6 Protein, Human (HEK293, His) is the recombinant human-derived SLITRK6 protein, expressed by HEK293 , with C-His labeled tag.
- Application
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Alternative Names
SLIT and NTRK-like protein 6; SLITRK6
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Species
Human
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Source
HEK293
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Tag
C-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H5Y7
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Expression Region
S27-S608
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Protein Length
Extracellular Domain
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Molecular Weight
89 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLITRK6 is a member of the SLITRK family of proteins, which are integral in neuronal development and synaptic function. This protein has garnered attention due to its involvement in neural circuitry, particularly in the context of brain development and certain neuropsychiatric disorders. SLITRK6 is thought to play a critical role in the regulation of axon growth and guidance, influencing the formation and maintenance of synaptic connections. Research has indicated that dysregulation of SLITRK6 expression may be linked to various neurological conditions, including autism spectrum disorders and schizophrenia. The study of SLITRK6 recombinant protein is essential for understanding its biological functions and mechanisms at the molecular level. By generating and characterizing the recombinant protein, researchers can investigate its interaction with other proteins, its influence on cellular signaling pathways, and its overall impact on neuronal health and disease. Furthermore, understanding the structure-function relationships of SLITRK6 may pave the way for therapeutic approaches targeting its dysregulation. Overall, the exploration of SLITRK6 serves as a promising direction in neurobiological research, with implications for diagnosing and treating neurodevelopmental and neuropsychiatric disorders.
